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The orthopedic surgeon who did TPO surgery on my first GSD recommended either 500 mg glucosamine and 400 mg chondroitin or 600/500. I don't quite remember and my notes are on my old computer somewhere. This was back in 1999/2000. Once SAM-E came out a lot of dog people started using that. it was the first that had the MSM in it.

I'm giving my soon-to-be 13 year old Zesty Paws Green-lipped mussel chews. I saw an increase in his desire to run a bit more after 30 days on it. He has been without it for 2 weeks and already seen a difference. He's back on it now.
 
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