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That happened to Molly last year. I came home from an outing and Molly had been in her crate and I noticed that her eye seemed swollen, so I kept on eye on her. About 10-15 minutes later I checked her again and her whole muzzle was swollen and she had all these lumps on the stop of her nose. I ended up taking her to the vet and they gave her a shot of epinephrine (sp?) and benedryl. By the time I got her to the vet the bumps started forming on her legs. She had a severe reaction to something and the only thing I can think of was a spider bite since she was crated while we were gone. She looked like Rocky Balboa after a fight
 
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