This is just an FYI ... my sweet Slider was diagnosed with Cauda Equina Syndrome (CES) and as time progressed he began to develop progressive rear end problems ... dragging his back legs. My vet x-rayed him and since his CES had not changed much, she diagnosed him with DM. When he passed away this past April, I wanted a necropsy done to determine if he had DM or not .. my vet didn't have the necessary tools to perform this type of necropsy, so I had a DM DNA test done (not the Dr. Clemons test, this one was done by DDC). Anyway, it turned out he was only a carrier ... only had one positive marker, the other marker was normal. So I assume all the rear end problems he had were due to the CES. (I lost 3 other dogs to CES all with the same symptoms but no testing was done). So there are diseases that mimic DM that really aren't, though it really doesn't make much difference since the results are the same, just the name is different.
New person here so bare with me. I have 2 shepherd sisters 7yrs.old Lacy and sheeba in great active health. 2 days ago was throwing ball out front lacy ran full stride missed ball and turned tight, I heard a small yipe, she came back with ball looking fine, both dogs finished playing came in house. My wife and I sat down to watch a movie, both dogs laid down. about an hour later Lace struggled to get up, her rear legs were wobbly and dragging. I took her right away to vet hospital, Lacy walked in wobbly dragging toes. Vet did x-rays hips, legs. no deformities, they gave me 3 sets of drugs and told me to watch her in the next couple days, if gets worse bring her back, the drive home was 30 miles by the time we got home 2:00 am she lost all functions of rear legs had to carry her in. the next morning took her back, the nuero- surgeon was in and evaluated lacy, right away DM was brought up, but they were perplexed at the quick onset, My wife and I were a mess since everything we looked at on the web. I told the surgeon to get Lacy in NOW for MRI and workup, costly but my girls are worth it. Glad I did, turned out to be a bulging disc in her neck causing rear leg paralysis. Lacy is recouping as we speak at the hospital and is bearing weight on rear, therapy for next 3 weeks, she comes home next week with or visits morning and evening. Her sister Sheeba slept next to her cage all night at home and still looks for her. she misses sister. The neurosurgeon said no more up on bed, when they jump down is the worst, they hit with front legs and jolts their head forward than back fast. If your dog is active and something like this happens suddenly, please don't think DM first. And if your baby has DM give them all the love and support you can give them, remember when you come home no matter what kind of day you had they wag their tail and love you no matter what. Prayers to all your tailwaggers. Patrick
It is a newish treatment that they have seen limited success with.
DM naturally plateaus throughout its progression and what seems to happen is that the treatment extends the duration of those plateaus in some dogs.
In a few they have seen what appears to be a recovery but then it returns with a vengeance.
It is also prohibitively expensive.
Much, much more research will be needed to call this a cure.
My condolences on your loss. I lost Sabi to DM.
Jax, Thanks for the link! Oops, looks like something went awry. No matter, I will contact her via her website. But thanks for your help. Edit to add: a message popped up saying it was no longer available.