Okay, I talked to my parents. Turns out I was misremembering a bunch of things - I thought he had lymphoma twice but turns out the first cancer was actually hemangiosarcoma and he got them both older than I was thinking. My mom writes:
Quote: Sasquatch was a mixed breed, about 70 pounds, approximately 12 years old in September 2004 when vet discovered abdominal mass preparing him for dentistry. Did surgery immediately, removed enlarged spleen. Biopsy revealed hemangiosarcoma.
Spleen had not ruptured, and ultrasound revealed no metastases but we opted to go ahead with chemo anyway. Was treated with adriamycin plus Zinecard every 2 weeks for total of 6 treatments. He did very well, no side effects, and was back to normal at the end of the treatment.
In March 2006 he developed lymphoma, with multiple enlarged lymph nodes in abdomen and chest. He had IV treatments with vincristine on March 10 and 17, and oral cytoxan for 4 days beginning March 25. The lymph nodes shrank dramatically and he seemed to feel much better.
At that point he would have had adriamycin according to their protocol but because he had been treated with it before, they gave him mitoxantrone instead on March 31. This essentially wiped out his bone marrow, and he developed an infection, for which he was hospitalized April 10-12 and given IV antibiotics. He had a blood transfusion on April 17, and after that improved over the next couple of weeks.
He had vincristine again on April 28, cytoxan on May 5-9, vincristine on May 12, and cytoxan again on May 17-21, and was to have had another 4 days of cytoxan beginning May 31 but began deteriorating markedly about that time. He was hospitalized after collapsing at home on June 4, and was euthanized on June 6.
She is looking for the report that lists the exact kind of lymphoma because she couldn't remember.
The main thing she wanted to pass on was that the first couple of lymphoma treatments went fine and the lymph nodes retreated dramatically, but unfortunately because he had already had his lifetime dose of the chemo they used the first time (it can cause heart damage if given too much) they then treated him with the mitoxantrone, which was the drug that did him in.
So even though his outcome wasn't actually that great, it was the last chemo drug that caused the big problem rather than the lymphoma, which actually responded pretty well to treatment.
She also reminded me that one of the (good) drugs they did give him for the lymphoma was cytoxan, which is the same thing my father had for his lymphoma and which knocked him into remission for more than 10 years. Sasq did fine with that one too.
I will post when I find out what kind he had.