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  Topic Review (Newest First)
04-18-2014 02:08 PM
wyoung2153 So glad that you figured this out!! From what I have read, when I thought Titan had this, it is rather manageable! So yay for that.

Regardless, have you thought of crate training her so she doesn't eat so many random things?
04-18-2014 01:54 PM
doggerel So sorry to hear that she has EPI. We thought our 9-month-old girl had it, for various symptoms similar to what you describe. It was a bad case of giardia instead, but I did a lot of reading on EPI in the meantime. Check out this wonderful site for more information about living with and managing EPI: They also have a forum. Good luck!
04-18-2014 01:45 PM
Heidigsd I have one suggestion that will help you along the way. Get a notebook and keep a journal for a while, that way you can go back to see what changes you made and how Shelby responded. I kept one for about two years and it helped a bunch.
04-18-2014 10:10 AM
Originally Posted by Kirwinjd View Post
Thank you so much for your suggestion to have Shelby tested for EPI.
You were right on the money. Now medication, I'm looking forward to
Seeing her gaining weight and me picking up dog logs instead of mule muffins
You're welcome. I am really sorry that Shelby has EPI but at least now you know what is wrong and can start treatment.

Harry and Lola has already given you great advise on how to get started with her treatment. I would also highly recommend joining epi4dogs!

The enzymes from the vet can be expensive but there is another option if you are interested. Enzyme Diane provides enzymes at a much lower cost to many EPI dogs. Enzyme Diane -

If you need help just let us know...I hope she responds to treatment soon and will become a member of the "Chunky Monkey" club
Chunky Monkey Club - EPI * Exocrine Pancreatic Insufficiency
04-18-2014 12:58 AM
Harry and Lola Sorry to hear she has EPI, but don't be worried about managing and treating her, some EPI dogs respond quickly and put on weight, others take a little longer and need 'tweaking' medication etc.

In Australia we use Creon 10,000 or 25,000 capsules which you can buy online, and give one before each meal.

I believe there are more options for replacement enzymes in the USA, so I suggest you join the eip4dogs website Forum - EPI * Exocrine Pancreatic Insufficiency and seek advice from the very experienced people there.

Also, I would suggest you treat her for SIBO at the same time you start giving replacement enzymes. Give her 1/4 tsp of Tylosin (Tylan) twice a day for 45 days.

I also suggest you treat her for low B12 levels at the same time, have your vet give her a weekly injection of generic B12 (not the multivitamin or complex one) for 6 weeks, then another shot 1 month later and put her on Wonderlab's B12 vitamin with Intrinsic Value (1 capsule daily)

Once you start treating her with the enzymes before each meal, sort out SIBO with a course of Tylan and keep her B12 levels high with the above injections and daily Wonderlab B12 capsule, you will see her weight increase, she will be less anxious and fearful and a lot happier and healthy.

Good luck and don't stress out too much, EPI is manageable
04-18-2014 12:41 AM
Originally Posted by Heidigsd View Post
Do you know if she has she been checked for EPI? Overview - EPI * Exocrine Pancreatic Insufficiency

Here is the test that is required, I would run it to rule it. Serum Trypsin-Like Immunoreactivity (TLI) - Texas A&M Veterinary Medicine & Biomedical Sciences
Thank you so much for your suggestion to have Shelby tested for EPI.
You were right on the money. Now medication, I'm looking forward to
Seeing her gaining weight and me picking up dog logs instead of mule muffins
04-14-2014 07:59 PM
K9POPPY I hope she doesn't have a blockage, but I agree with the others, to have her checked for EPI. I hope also that she gets a good check-up!!! Best wishes for her- Bob
04-14-2014 05:24 PM
huntergreen EPI would explain why she is eating lots of "stuff" and weight loss. might want to see how soon you can get to the vet.
04-14-2014 01:36 PM
_Zero_ I'm with Heidigsd and Harry and Lola here-- get her checked out for EPI. It is common in GSDs, but often veterinarians do not have experience with the disease and do not understand the proper testing procedures or treatment protocol.

The test for EPI is a blood test that must be done after AT LEAST a 12 hour fast. If you do test for EPI make sure your dog has had no food (water is fine) for at least 12 hours. The values read from the bloodwork should be cTLI, cobalamin, and folate.

EPI stands for exocrine pancreatic insufficiency. The pancreas stops producing the necessary enzymes for digesting food. Since food goes through the digestive tract poorly digested, the dog does not receive proper nutrition and rapidly loses weight. This leads to constant diarrhea/loose stools, malnutrition, and can have other symptoms, such as pica (eating a bunch of random things the dog shouldn't). Further, undigested food in the intestines promotes growth of undesirable bacteria.

If your dog does have EPI you'll likely have to put her on a 45-day course of antibiotics (Tylan is usually the best choice) and permanently add digestive enzymes to her food. Some dogs also need B12 vitamins or B12 injections.

I strongly encourage you to check out the website Heidigsd listed:

Overview - EPI * Exocrine Pancreatic Insufficiency

and read through the symptoms, testing protocol, and treatments BEFORE you take your dog to the vet. I'd also recommend joining the forum there and telling those folks what you've experienced with your dog. They are an active and very supportive community that can walk you through the steps of testing for EPI, and, if she's diagnosed, treating it.
04-13-2014 10:51 PM
Originally Posted by Harry and Lola View Post
As Heidigsd said - ask the vet to test her for EPI, is a simple blood test and if positive you will need to give her replacement enzymes before each meal and probably treat her for SIBO as well.
We'll definitely mention it to the vet tomorrow. Thank you
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