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Thread: Switching epilepsy medications - advice, opinions, experiences welcomed! Reply to Thread
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Topic Review (Newest First)
03-09-2014 08:37 PM
GatorBytes
Quote:
Originally Posted by LifeofRiley View Post


I really respect the fact that you are curious. And, I hope that any information I am able to provide via this thread is helpful to people who browse this forum/thread in the future.
As well, this read about nutritional deficiencies, minerals, amino acids, etc

The Role of a Natural Healthy Diet in the Management of Canine Epilepsy

Wouldn't it be nice to find something that promotes the health of the kidneys and liver instead of go to conventional drug treatment that kills these organs and only manages the disorder??
03-09-2014 08:17 PM
anitram My first rough Collie was diagnosed with epilepsy when he was 3. He actually had his first seizure when he was 2, but then nothing for a year so at that point the vet thought maybe it was a freak event or maybe he'd eaten some grass on a lawn of a person who had use pesticide (it was June and lots of people are way too lazy to put up lawn signs).

Eventually he was put on phenobarb and I have to be honest, nothing else ever worked for him. He always ended up back on the phenobarb and the dosages increased, then increased. We unfortunately had to put him to sleep when he was almost 8. At that point he'd been on phenobarb for nearly 5 years, he had started showing decreased kidney function and he was having unstoppable seizures every other day so he had no quality of life left to speak of.

However, he did really well on the phenobarb from age 3 to about 7-7.5. By which I mean that he had one seizure maybe every 3-4 months. It was hard to watch and he felt terrified and also very ill for the next 24 hours but otherwise he was doing fine, was happy, active, etc. So while it has side effects for sure, it also has the ability to buy you quite a few really good years with your dog.

I wish you all the best, it's not easy but it sounds like you're really doing everything right for your buddy.
03-04-2014 11:32 PM
LifeofRiley
Quote:
Originally Posted by gsdsar View Post
What????? You were more concerned about your own girls health than asking theoretical questions to satisfy the curiosity if a stranger on a web board. Shame on you!!!!(read in full sarcasm please!!!)

Lol.Sent from Petguide.com Free App


I really respect the fact that you are curious. And, I hope that any information I am able to provide via this thread is helpful to people who browse this forum/thread in the future.
03-04-2014 10:17 PM
Bear GSD Sorry, I looked back on the thread and you mentioned that you had looked into Keppra. We did have to administer 3x a day, but it wasn't an issue for us.
Keppra is expensive but you can get it at Costco for a little less money.
03-04-2014 10:11 PM
Bear GSD My girl was put on a combo of pheno and Keppra. I know that it is also used to treat humans and it is a lot safer on the liver than pheno.
She was having static/cluster seizures and the medication did seem to help for a while.
Good luck, it's so hard to see them through seizures.
03-04-2014 08:41 PM
gsdsar
Quote:
Originally Posted by LifeofRiley View Post
Yes, I was understandably much more pre-occupied on what the recommendation was for my dog than on asking additional questions about the transition protocol. But, I have to say, I did feel like kicking myself afterwards for not asking more questions about that during the appointment!!! I am also curious and I knew that you would be too!



We have another appt. in 3 weeks, I will be sure to ask at that time and share back

What????? You were more concerned about your own girls health than asking theoretical questions to satisfy the curiosity if a stranger on a web board. Shame on you!!!!(read in full sarcasm please!!!)

Lol.


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03-04-2014 08:34 PM
LifeofRiley
Quote:
Originally Posted by gsdsar View Post
I would love to know how your Neuro would prefer to have dogs switched. It's very interesting to me. Sent from Petguide.com Free App
Yes, I was understandably much more pre-occupied on what the recommendation was for my dog than on asking additional questions about the transition protocol. But, I have to say, I did feel like kicking myself afterwards for not asking more questions about that during the appointment!!! I am also curious and I knew that you would be too!

We have another appt. in 3 weeks, I will be sure to ask at that time and share back
03-04-2014 08:28 PM
gsdsar I am so sorry to hear that. I hope your boy does well now back on the Pheno. We have to do what is best for each individual dog. And each drug does not work as well on each dog.

Yeah the switch over is weird. I would love to know how your Neuro would prefer to have dogs switched. It's very interesting to me.


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03-04-2014 08:21 PM
LifeofRiley Update: The transition failed. Riley has been having more seizures in shorter periods of time that at any other point since his initial diagnosis.

We were at the neurologist today and the decision was made to stop the Zonisamide and re-institute full dosage of the Phenobarbital…. actually, a higher dosage.

@gsdsar - The neurologist had an interesting pov on the transition protocol that is being recommended to general practice vets… i.e., he doesn’t like it! He mentioned that the interaction between the two drugs interfere with their respective effectiveness – much like what you said in an earlier post.

While I did not get all the details, he inferred there is a much better way to approach transitioning from Pheno to Zonsi. I did not get all the details because, in our case, based on lots of other information shared during our appointment, he thinks that even with a good transition protocol, my dog is not responding well to the Zonisamide, so we are tapering off of it.
01-30-2014 10:31 PM
GatorBytes Was he ever tested for MDR1 mutation. Ivermectin can build up in the brain.
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