Intervet Inc, 29160 Intervet Lane, PO Box 318, Millsboro, DE 19966, USA.
A challenge-of-immunity study was conducted to demonstrate immunity in dogs 3 years after their second vaccination with a new multivalent, modified-live vaccine containing canine adenovirus type 2 (CAV-2), canine parvovirus (CPV), and canine distemper virus (CDV). Twenty-three seronegative pups were vaccinated at 7 and 11 weeks of age. Eighteen seronegative pups, randomized into groups of six dogs, served as challenge controls. Dogs were kept in strict isolation for 3 years following the vaccination and then challenged sequentially with virulent canine adenovirus type 1 (CAV-1), CPV, and CDV. For each viral challenge, a separate group of six control dogs was also challenged. Clinical signs of CAV-1, CPV, and CDV infections were prevented in 100% of vaccinated dogs, demonstrating that the multivalent, modified-live test vaccine provided protection against virulent CAV-1, CPV, and CDV challenge in dogs 7 weeks of age or older for a minimum of 3 years following second vaccination.
By failing to make a statement of the known science, by failing to require longer DOI data from manufacturers, and by failing to remove one-year vaccines from the market, the VMD is facilitating the unethical practice of annual vaccination.
The WSAVA guidelines recommend: “We should aim to vaccinate every animal, and to vaccinate each individual less frequently.” These international guidelines also recommend that, “we should aim to reduce the ‘vaccine load’ on individual animals in order to minimise the potential for adverse reactions to vaccine products”.
More Documentation Of Over-Vaccination Risks