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DutchKarin 06-11-2014 10:55 AM

Eosinophilla, parasites, allergies?
Tygo has been ill the last couple of weeks. A little back ground on my Dutchie... he has never had the most consistent poops, varying from good to pudding. Some time ago he started losing weight, and I did not really notice, thinking that it was just variation in the scales. Then he developed some vomiting, usually of water, and at the first sign of blood in his loose stools I took him in. He had dropped from 63 to 58 lbs. A couple of times he refused food, but an anti-nausea pill had him up and running.

Vet did a full work up and all results normal except for eosinophilla, a high level of a white blood cell often associated with parasites, drug reaction, and allergies. So Tygo has been through a week of metronzidole, amoxicillin, and was wormed with panacur. His energy and attitude are normal and high.

He has been off the medication for a week. His stools now tend to start out good but go way loose and in the morning he has 3 bowel movements all progressively looser. I am now in the process of shifting him slowly to Natural Balance Duck and Potato food (from TOTW Boar) and treats as a food trial. My intention is to do this for 12 weeks. I know it is not the best food out there but that is what I decided to do, given, unfortunately that he has been on so many different proteins out there. I am also giving him a probiotic and digestive enzymes. I have stopped fish oil for now.

I just wanted to see if anyone has dealt with this and any recommendations in addition to what I'm doing.

Thank you everyone.

scubajoe 06-11-2014 11:29 AM

Did the vet do any other labs? High blood count could mean other things as well, so maybe best to rule some of them out.

DutchKarin 06-11-2014 11:43 AM

Did full CBC, tested liver enzymes, tested pancreas, adrenal function, tested for giardia. All normal or negative.

Muskeg 06-11-2014 03:26 PM

Could it be whipworms? Whipworms often don't show up in a fecal exam. You need multiple treatments with Panacur (3) to get rid of them. My GSD (an adopted stray) had terrible bouts of bloody diarrhea, loss of appetite, and was very skinny. The vet finally saw whipworms in the fifth fecal exam, and after three rounds of Panacur, all that stopped. I remember thinking my dog just had a bad digestive system, but after treatment, she has been totally fine for years.

_Zero_ 06-11-2014 05:42 PM

Sounds a bit like what my dog went through last year:

Has he been tested for EPI? The symptoms don't match exactly, but it might be worth reading up on it a bit, if you're not familiar with it, to see if anything strikes a chord:
Overview - EPI * Exocrine Pancreatic Insufficiency

A food trial is a very good start, if he hasn't had duck before. Remember to give nothing but the kibble (i.e. no other treats, bones, etc.) to ensure that all his GI tract is exposed to is the new protein source.

Have you considered Tylan? Many people here on the forum have had excellent success with Tylan for large bowel/colitis issues. It's an antibiotic. You can buy it without a prescription online. It comes in a 100g powder form. The dose for a 60-85 pound dog is 1/4 tsp twice daily: SID (SIBO) - EPI * Exocrine Pancreatic Insufficiency. It is very bitter so many buy empty gel caps at the health food store and fill them with the powder, or mix with a bit of canned food if your dog will tolerate it (NB has canned versions of all their LID foods).

Based on what I went through with my own dog, my advice would be to continue the food trial and start your dog on Tylan. If his stools improve, continue giving the Tylan for 45 days total. And consider looking into EPI and see if Tygo's symptoms match up at all- if they do, it might be worth it to have the blood test, just to rule it out.

When he was on the meds your vet prescribed, did his stools improve?

DutchKarin 06-11-2014 05:54 PM

Thank you Zero. I'll keep EPI on the radar. This is the test he did have:
Pancreatitic Lipase Isoenzyme (test for pancreatitis): normal
Probably not the right test?

I will also ask about Whipworms. He has been wormed twice in 2014. But I'll keep that on the radar as well after reading about it.

I have Tylan powder left from my old dog that had chronic colitis. I'm familiar with it and will give it a try but first I'm going to see what happens when he is completely on the duck and potato. His stools have been good today.

Thank you for your ideas.

_Zero_ 06-11-2014 07:09 PM

The EPI test is different than that for pancreatitis (PLI). It is a TLI test (trypsin-like immunoreactivity). Most people also recommend measuring cobalamin and folate levels at the same time as an indication of small intestinal bacterial overgrowth (SIBO) which usually accompanies EPI.

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