Your dog will be fine. The studies that are usually quoted, don’t actually have any statistical significance. There is basically no “control group.” And the increases and decreases in risk for disease X is usually less than any acceptable p-value for a scientific study. If you read the studies, the language is usually very ambiguous and rarely are actual numbers told.
Most of the causations are actually just correlations…but correlation does not ever prove causation and because of the wide variety of other environmental factors that are not controlled in the studies, its hard for me to believe that their conclusions are valid.
I’ll tell you that your dog will probably not be as masculine looking or filled out as an intact male…but that’s all appearance and has very little to do with health. I have a female right now that was spayed early (I didn’t own her). She does look much more “puppy like” than her sisters (from the same litter). I could care less. She’s a wonderful dog, has all the working ability and drive that her sister’s have, and I don’t’ have to deal with heat cycles and my male looking his head every 6 months.