Swollen nose

[Anubis_Star]

I wil stake my career on the fact that I 110% fully believe it was NOT the benadryl ! Every VETERINARY referance ive looked at , even my own veterinarian I talked to at work last night , no where has it ever been indicated that benadryl will cause an arrythmia. there is a difference between people becoming hyper reactive on drugs like bendaryl (thats a known side effect) and a drug actually causing cardiac irregularities. Im sorry , I believe a vet with over 20 years experience over one website thats not even a medical board. so there is no reason the vet should of said it was the benadryl because it wasnt.

You stated it could be an allergic reaction that caused it. True , but I would think its an allergic reaction to the swollen spot on the muzzle. And no we dont wait until dyspnea from swollen air ways occurs. We treat as soon as we see facial swelling to PREVENT dyspnea. As far as advising for medications over thr phone ,usually we would just say to come in as it can turn serious but in certain circumstances theres no need to believe a young healthy dog would have cardiac disease. Its an otc drug given frequently and in all honesty they probably recommended an extremely low dose. 25mg im guessing ? Maybe even just 5mg

Excuse the spelling im on my moms tablet and I HATE it

[1sttimeforgsd]

Best wishes that your boy's problem will be easily fixed. I will be keeping him in my prayers.

[evybear15]

The e-vet said that, given his size, it would be safe to give him up to 50mg of Benadryl. As he had never had it before, I wanted to give a smaller dosage first (25mg), and see how he did, but was prepared to give him more if the swelling went up.

I would think that if it were to cause a hyperactive situation, the heart rate would be elevated, but not necessarily irregular. I, personally, have something called "inappropriate sinus tachycardia" - my heart rate is extremely sensitive and jumps up quite easily. Prior to finding the right meds, it wasn't uncommon for my HR to be over 200 during exercise. They actually stopped the one stress test that I have had, because they were getting anxious about it, despite the fact that the EKG was showing no issues, and I was feeling fine (just tired). It's just speedy, and is over-reactive to movement. Theoretically, I'll "grow out of it."

Baxter was acting like his typical goofball self last night and this morning, which reassured me a bit. Only a few hours of work left, and then off to fetch him and head to the opposite side of town for his appointment.

[GatorBytes]

Originally Posted by Anubis_Star

I wil stake my career on the fact that I 110% fully believe it was NOT the benadryl ! Every VETERINARY referance ive looked at , even my own veterinarian I talked to at work last night , no where has it ever been indicated that benadryl will cause an arrythmia. there is a difference between people becoming hyper reactive on drugs like bendaryl (thats a known side effect) and a drug actually causing cardiac irregularities. Im sorry , I believe a vet with over 20 years experience over one website thats not even a medical board. so there is no reason the vet should of said it was the benadryl because it wasnt.

How about Pfizer then?

2. Cardiovascular System: Hypotension, headache, palpitations, tachycardia, extrasystoles
http://www.pfizer.com/files/products/uspi_benadryl.pdf

[GatorBytes]

Histamine exerts a series of actions upon the
cardiovascular system. Thus, through mediation of
the H

1 and H2 receptors, histamine increases vascular
permeability and induces hypotension, with refl ex
tachycardia. In turn, at heart muscle level, histamine
action upon the H1 receptors induces an increase in
atrioventricular node conduction, while the H2 receptors
mediate positive chronotropic and inotropic effects
[3]. The H1 antihistamines, as inverse agonists, exert
the opposite effect, with partial countering of the
aforementioned actions. However, the main concern in
relation to the cardiovascular safety of the antihistamines
refers to their cardiac arrhythmogenic potential. A review
is provided below of the principles and clinical particulars

of these worrisome adverse effects

[msvette2u]

Where is this info found? I see no reference? What is it in regards to?

Originally Posted by GatorBytes

Histamine exerts a series of actions upon the
cardiovascular system. Thus, through mediation of
the H

1 and H2 receptors, histamine increases vascular
permeability and induces hypotension, with refl ex
tachycardia. In turn, at heart muscle level, histamine
action upon the H1 receptors induces an increase in
atrioventricular node conduction, while the H2 receptors
mediate positive chronotropic and inotropic effects
[3]. The H1 antihistamines, as inverse agonists, exert
the opposite effect, with partial countering of the
aforementioned actions. However, the main concern in
relation to the cardiovascular safety of the antihistamines
refers to their cardiac arrhythmogenic potential. A review
is provided below of the principles and clinical particulars

of these worrisome adverse effects

[GatorBytes]

H1-antihistamines: inverse agonism, anti-in... [Clin Exp Allergy. 2002] - PubMed - NCBI

Benedryl = H1 antagonist (diphenhyramine)

[GatorBytes]

Originally Posted by msvette2u

Where is this info found? I see no reference? What is it in regards to?

google it ~ h1 antihistamine + cardiovascular

[evybear15]

The verdict is in, and Baxter is going to be just fine. They did hear a slight murmur, but it is either stress-induced, or a slight enough congenital issue that it won't affect his long term health. To determine that they would need an echocardiogram, but they didn't feel like he NEEDED one.

Although a bit anxious about being at a new location, he was the perfect gentleman and made sure to give the cardiologist and her tech lots of smooches when they would let him.

[GatorBytes]

Sounds like good news I guess? slight murmur...

You may want to get proactive in suppliments - Omega 3 (fish body oil), is for the heart, Q10 foods (wouldn't suppliment if you can get through foods), magnesium...look into this

WHFoods: coenzyme Q

Magnesium Deficiency in Dogs | petMD

also colostrum

Altered immunity may be the hidden cause of atherosclerosis and cardiovascular disease. For example, a type of Chlamydia has been associated with arterial plaque formation in over 79% of patients with heart disease. A recent New England Journal of Medicine article (36) concluded that heart disease is the result of immune sensitization to cardiac antigens. Immune system mediated injury results in myocarditis with lymphocytes and macrophage being the predominant infiltrating cells. Colostrum PRP may have a role in reversing heart disease very much like it does with allergies and autoimmune diseases. Additionally, IgF-1 and GH in colostrum can lower LDL-cholesterol while increasing HDL-cholesterol concentrations. Colostrum growth factors promote the repair and regeneration of heart muscle and the regeneration of new blood vessels for collateral coronary circulation.

http://www.synertekcolostrum.com/ind...ural-medicine/