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#21 (permalink) |
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Banned
Join Date: Mar 2006
Location: Beautiful Pacific NW
Posts: 11,005
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Huh...???
Experts agree that canine Parvovirus is closely related to Parvoviruses that affect other animals. Where the virus originally came from remains unknown, but it is possible that it is a mutant from another Parvovirus that affects other species of animals. Man is not known to be affected by canine Parvovirus. Since its first appearance in 1978, canine Parvovirus has spread to every continent in the world, probably the result of the hardy nature of the virus. Parvovirus Are you saying diseases don't mutate...?? Or that natural selection (were we to never vaccinate) would have taken care of the virus? Kinda difficult to say with any degree accuracy, since virii are always mutating... Canine Parvovirus (CPV) was first observed in 1978, and is considered a completely new pathogen for dogs. No conclusive origin of CPV is known, but it is postulated that CPV arose by natural genetic mutations of the feline panleukopenia virus (FPLV). CPV and FPLV are more than 98% similar in nucleotide and amino acid sequence, but they can be easily be distinguished from each other based on biological properties. These biological differences translate into very minor genetic differences, however, as analysis has shown that even a difference as significant as the canine host range is determined by a three or four sequence difference in the viral protein gene. CPV is an important example of virus shift in host range and is being studied as a possible model for how new viruses originate... CPV is an important example of virus shift in host range and is being studied as a possible model for how new viruses originate. cat-dog parvovirus |
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#22 (permalink) | |
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Banned
Join Date: Mar 2006
Location: Beautiful Pacific NW
Posts: 11,005
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Quote:
Somehow these threads always wind up wayyyy off topic. |
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#29 (permalink) | |
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Knighted Member
Join Date: Jul 2012
Location: Southern Ontario
Posts: 2,140
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Quote:
Parvovirus Canine parvovirus is very similar to the long known feline panleukopenia virus (FPV). Soon after its appearance, parvo was classified as a mutation of FPV – in fact, the first vaccines used against parvo were FPV vaccines. Prior to the parvovirus outbreak, the only widely-used vaccine for dogs was distemper. At some point, cats’ kidneys were used to develop the distemper vaccine and this was shipped around the world and injected into dogs. If Clare Thompson is right, the distemper vaccine was grown on cat kidney cells and the cats were infected with FPV. Another possibility is that cats that were vaccinated for FPV shed that vaccine through their feces – a very real risk with modified live vaccines. The feline parvovirus could have easily mutated into canine parvovirus. In Vaccines For Biodefense And Emerging And Neglected Diseases, the authors state that the trouble with modified live vaccines is: “…there is a high probability of back mutation and reversion to virulence once introduced to the animals.” Regardless of how canine parvovirus originated, it is well accepted that it is a man-made disease and it is the result of vaccination, either for canine distemper or FPV. This much is obvious because the outbreaks were sudden and massive and they first surfaced in countries that regularly vaccinated dogs and cats.
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He is your friend, your partner, your defender, your dog. You are his life, his love, his leader. He will be yours, faithful and true, to the last beat of his heart. You owe it to him to be worthy of such devotion. - Unknown |
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#30 (permalink) | |
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Knighted Member
Join Date: May 2002
Location: USA
Posts: 2,145
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