No problems, it just never worked for long
Our 9 yr old White GSD had infections off and on for three years. On the advice of our Vet, we had them removed and she has been much more comfortable, and none of the staining. Our Vet used several treatments with antibiotics before we had them removed, but never had any issues with administering the medication. (Pyzon is very calm at the vet, don’t ask me why)
"Dogs were put on Earth to demonstrate unconditional love, cats are here to teach us we aren't that **** important"