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Old 05-10-2010, 04:14 PM   #1 (permalink)
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Unhappy zimecterin for heart worm

I've been using this for worms and heart worms for almost 5 yrs and I have gave Bella 1 dose and she seems ok and then I found this should I stop using it on Bella? I'm worried now

Ivermectin Poisoning from Parasite Prevention Drugs in Dogs | beingstray.com
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Old 05-10-2010, 04:30 PM   #2 (permalink)
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Sounds to me like the article is talking about dogs who have the mutant/mutant MDR1 gene. If Bella hasn't had any of the symptoms in 5 years she probably won't have one, but if it would make you feel better, you can get her DNA tested to see if she has the mutant/mutant condition.

I assume since it's a horse product you can give an overdose, but as long as you continue giving the same dosage you always give it should be okay.
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Old 05-10-2010, 04:43 PM   #3 (permalink)
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Bella is only 6months old and has had only one dose I've only had her one month. Its the other dogs I've been giving for almost 5 yrs. But therir not GSDs eather. That's why I'm worried. If it was gunna hurt her would that fisrt dose indicate she's ok ?
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Old 05-10-2010, 04:46 PM   #4 (permalink)
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I don't know - the one puppy I know of who had a severe reaction almost died from just one dose. But you can get your puppy the DNA test if you're worried.
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Old 05-10-2010, 04:51 PM   #5 (permalink)
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I would get ivomec, and stop using zimectrin. The problem with the paste wormers is the ivermectin within is not consistent. Its very easy to give a dog a dose thats too low to be therapeutic or too concentrated. The paste livestock wormers are meant to be given to very large animals, when dosing it out to use with small animals you should empty the entire tube into something and mix thoroughly before dosing so the dosage is consistent throughout the paste.
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Old 05-10-2010, 05:04 PM   #6 (permalink)
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Ohh Bellas first dose was almost a month ago its almost time for the 2nd dose but now I'm iffy on giving it.
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Old 05-10-2010, 06:27 PM   #7 (permalink)
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I have an aussie who is mutant/mutant to the mdr1 gene..Ivermectin could literally kill her.

I give Interceptor to all my dogs.
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Old 05-10-2010, 07:13 PM   #8 (permalink)
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I really like using ivomec because its pure ivomectin and no additional wormers. Its also much cheaper! There are generic ivomectin liquid injectibles as well for even cheaper. The dosage (for 1% ivomectin solution) is 1/10th cc per 10 lbs of body weight. Its also much more exact to the body weight while heartgard and others are dosed in ranges.

For breeds that are prone to the MDR1 gene you can get them tested. Since she was fine with the zimectrin I doubt she has the gene. Its more common in the collie breeds.
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Old 05-10-2010, 08:05 PM   #9 (permalink)
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I use the zimectrin paste but you do have to be careful. The concentration of ivermectin is higher than that of Interceptor and other dog products, so it's not as simple as a weight/volume conversion. Also, like Lin said the zimectrin paste is meant to be given all at once. I actually squeeze it all out and mix it. There's a lot leftover but it's still cheaper to use one tube (and toss the rest) each month for $7 total than $6 per Interceptor pill per dog.

Lin where do you get the 1% ivomec? Is that a shot or what? I would like something I can do myself with a more dog-accurate concentration and not have to throw so much away each month.
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Old 05-10-2010, 08:14 PM   #10 (permalink)
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The 1% ivomectin solution is made to be a shot for livestock but you give it orally to dogs. You pull out the dosage with a needle and syringe, but then I inject it into something like bread that is absorbent and follow it up with something REALLY yummy since it tastes awful. You can order it online, or pick it up from a local feed store (tractor supply co carries it.) Make sure to not get ivomec plus though, it has an additional ingredient.

For ivomectin paste you can go way cheaper than that, many places sell generic brands of ivomectin paste wormer for as cheap as $1 something a tube (though that cheap may only be for bulk orders.) I've bought them in bulk before for my horses, and when making a gift box for the Indiana Horse Rescue.
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