I can think of a few breeds (chow,akita,presa, any LSG to name a few) I would have reservations over, TBH. Provided proper research and such, I'd be more than happy to welcome the new furkid. I do not dislike any breed, but some have care requirements that need a little more thought beforehand IMO.
Shenzi the GSD
Scruffy the woofing terror
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Zira “To the well-organized mind, death is but the next great adventure.” -J.K Rowling