Delgado puked on his first car ride with me and never has since.
Try again with a short ride and see how it goes, if he pukes again you may have a issue. Start slow and work your way up. So day 1 just have them sit in the car while it's not moving, then if that goes well day 2 has you driving once around the block, etc etc
Delgado will whine sometimes on car rides and I find just cracking the window down partly quiets him down right away, I don't know if it's actual car sickness but I know it helps for humans and figure why not.
Jasmine - Female Miniature Poodle - born Aug 15, 2010
Loker Delgado Von Stalworth - Male GSD - born Jan 26, 2012
Koda & Zazu - 5 year old male cats
Alex - Male Cocker Spaniel (rescue) - RIP Cuddlebug 2007-2010