I wouldn't be surprised if he felt the need to stay by your wife because she was sick.
When I was sick, Hans was by my bed and refused to leave my side no matter what was going on in the house.
Just shooting from the hip...
"She turned the TV on and and the pup was laying on the floor on her side of the bed."
Was the pup able to access the crate if he wanted...door open?
If so, maybe the dog chose this place on the floor on her side of the bed as a preference over the crate?? Maybe the dog sensed your wife's ailing and chose to stay near exhibiting a bit of a protecting mentality??
Perhaps, the dog's vocalizations and odd behavior is simply saying he'd rather sleep on the floor on your wife's side of the bed?? All guesses of course.
Have you ever left the crate door open at night with the bedroom door closed and seen where he prefers to sleep?
I've never done the crate thing with any of my dogs so I cannot speak with any experience on the behavior my dog's have demonstrated with any commonality to yours in this particular regard.
I have never left the crate door open at night. We have always crated the pups until they were older. Keeps them out of trouble. We have witnessed him going into the crate on his own on occasion putting toys in there, taking toys out, laying down, etc. He seems to know it's his crate/bed. I suspect if I left the crate open at night he would likely lay on the floor by the door to make sure we didn't escape with out him knowing
I have sleep issues and if I wake up, I have a heck of a time going back to sleep, if I'm able to at all. I don't want him deciding it's play time at 2am.
My wife and I did discuss the fact that we will likely graduate him from the crate younger than most of our other dogs. Simply his size alone (16 weeks, 45 lbs).... And the fact he is a "wicked awesome" pup. (sorry, I have been talking to people from Boston this week). He has yet to damage anything other than a couple dog toys.