SOME dogs get a little diarrhea from Adequan (my dog didn't but he was not sensitive that way). The loading dose is 2x/week for 4 weeks and then you determine frequency from there (monthly, 3 weeks, whatever). I saw results aftr about 4 shots - his back end didn't sag and if I pressed on it, didn't go down. I thought the stuff was amazing.
I like the Fresh Factors - wonder why they said that.
Good luck with the Adequan, let us know how it goes!